Everything about ceesdekker
Everything about ceesdekker
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Nanotechnology delivers a range of possibilities to contribute to biology. Listed here I will current examples the place nanofabrication – the opportunity to make confined buildings with Proportions at will – is made use of to look at the biophysics of one molecules and cells. I'll existing some illustrations from our lab:
Human Rad51 filaments on double- and solitary-stranded DNA: correlating standard and irregular varieties with recombination purpose.
The following articles are merged in Scholar. Their put together citations are counted just for the first post.
Non-equilibrium folding of unique DNA molecules recaptured as many as 1000 situations in the sound point out nanopore
2015, discovery that condensin can be a highly versatile protein composition; and first detection of DNA knots employing nanopores
Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en satisfied 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
You are a Christian. If you could make such a synthetic cell, would you be one particular action nearer to God, or would the position of God have diminished rather all over again?
He also found time to jot down quite a few guides, send out Just about forty thousand tweets and direct a successful research team at Delft College of Technological innovation. ‘It doesn’t come to feel like perform’, he states. ‘I’m just terribly curious.’
The rotors harness energy from the nanoscale h2o and ion stream that is definitely created by a static chemical or electrochemical probable gradient from the nanopore, which happen to be founded via a salt gradient or utilized voltage, respectively. These artificial nanoengines self-organize and operate autonomously in physiological circumstances, suggesting ways to developing Electrical power-transducing motors at nanoscale interfaces.
‘The fantastically refined way in which aspects in mother nature perform under no circumstances ceases to amaze me. If we solve the puzzle of how daily life arrived into being, I count on that my amazement within the complexity of creation can have greater and with it my awe for the greatness in the Creator.’
Given that 2000 he moved to solitary-molecule biophysics and nanobiology, with investigate from studies of DNA loop extrusion and supercoiling to DNA translocation by means of nanopores. Far more a short while ago his research has focused on learning chromatin construction and cell division with microbes on chip, while he can also be trying to eventually Create artificial cells from The underside up.
2001, discovery of single-electron transistors at place temperature depending on nanotubes; realization of initial logic circuits with carbon nanotube equipment; and discovery on the molecular structure of https://www.ceesdekker.net DNA maintenance enzymes with AFM
Enable’s initially search back at the moment once you decided to shift your concentrate from superconductivity and nanotubes to biology at the end of the nineteen nineties.
Ultimately, I will briefly sketch many of our Strategies to check out the making of synthetic cells, particularly our first ways to determine synthetic mobile division.